1Cademy - Haplotype Network Results in SARS-CoV-2 Genome Analysis of Japanese Travelers in Nile River Cruise

Rationale for SARS-CoV-2 Genome Analysis of Japanese Travelers in Nile River Cruise

Haplotype Network Results in SARS-CoV-2 Genome Analysis of Japanese Travelers in Nile River Cruise

P1 isolate was closely related to European isolates. P2-1 and P2-2 traveled on the same cruise as P1 and both isolates were identical to the P1 isolate.
P3-1 and P3-2 also visited Egypt and were aboard the same flight to Cairo as P1. Despite traveling on a different cruise both P3-1 and P3-2 eventually displayed symptoms and were confirmed positive.
Both genome sequences associated with the P3-1 and P3-2 isolates were distinct from the P1, P2-1 and P2-2 cluster, but only differed by a single SNV.
Individuals P4-1 – P4-4 visited Cairo days after the previously mentioned clusters, but tested positive with a distinct haplotype.
P4-5 – P4-8 had no history of contact with the aforementioned groups but were fairly similar in haplotype. P4-5 is a coworker of both P4-6 and P4-7. Moreover, P4-8 is the mother of P4-5, which suggests that P4-5 is the original source.
P5-1 was the only individual in his cluster that traveled to Egypt, but upon returning subsequently infected his daughter (P5-2) and sister (P5-3).

5 years ago

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Figure 2: Haplotype network using genome-wide single-nucleotide variations in SARS-CoV-2 Genome Analysis of Japanese Travelers in Nile River Cruise
Figure 3 in SARS-CoV-2 Genome Analysis of Japanese Travelers in Nile River Cruise